A simple method for fallopian tube sperm perfusion using a blocking device in the treatment of unexplained infertility.
نویسندگان
چکیده
OBJECTIVE To evaluate the efficacy of fallopian sperm perfusion (FSP) using a new method similar to the FAST system in comparison with standard intrauterine insemination (IUI) in patients with unexplained infertility. DESIGN Prospective, randomized, controlled study. SETTING Assisted conception service in a University Hospital. PATIENT(S) Women with unexplained infertility undergoing controlled ovarian hyperstimulation (COH). INTERVENTION(S) After hCG administration, patients were randomized to either standard IUI or FSP. The women received the same treatment in the first and all subsequent cycles. A maximum of three cycles was performed. Intrauterine insemination was performed using a standard method, and fallopian sperm perfusion was performed using a commercial device for hysterosalpingography and tubal hydropertubation. MAIN OUTCOME MEASURE(S) Clinical and ongoing pregnancy rates. RESULT(S) A total of 132 cycles was completed: 66 IUI cycles and 66 FSP cycles. In the IUI group, there were 5 ongoing pregnancies, giving a pregnancy rate of 7.6 per cycle and 15.6% per patient; in the FSP group, 14 ongoing pregnancies occurred, giving a pregnancy rate of 21.2% per cycle and 42.4% per patient. The prevalence of multiple pregnancies, miscarriages and ectopic pregnancies was similar in the two insemination groups. Fallopian sperm perfusion was easy to perform, and no case of sperm reflux was observed. The procedure was well tolerated and no complications were observed. The costs were comparable with standard IUI. CONCLUSION(S) In the treatment of couples with unexplained infertility, the method for fallopian sperm perfusion described yields higher pregnancy rates than IUI, with no significant increase in costs or complications. However, these results need to be confirmed in larger studies before replacing IUI with FSP as standard practice.
منابع مشابه
The comparison between Intrauterine Insemination and Fallopian Tube Sperm Perfusion Using FAST®System in Patients with Unexplained Infertility
BACKGROUND Controlled ovarian stimulation (COH) with intrauterine insemination (IUI) is commonly offered to infertile couples with patent fallopian tubes because it is simple, non-invasive and cost-effective technique. Another non-invasive method is fallopian tube sperm perfusion (FSP). This study was performed to compare the relative efficacy between FSP using fallopian sperm transfer (FAST) s...
متن کاملThe comparison between Intrauterine Insemination and Fallopian Tube Sperm Perfusion Using FAST
متن کامل
Is the fallopian tube better than the uterus? Evidence on intrauterine insemination versus fallopian sperm perfusion
Fallopian tube sperm perfusion (FSP) is in short comprised of mild ovarian stimulation with the aim of maturing 2 follicles, ovulation induction and insemination using a large volume (4 ml) of inseminate. Perfusion studies demonstrated that with this large volume, the inseminate will fill the uterine cavity, flow through the fallopian tubes and some of it will end up in the peritoneal space. Th...
متن کاملQuestioning the efficacy of Fallopian tube sperm perfusion.
The aim of this work was to compare the efficiency of standard intrauterine insemination (IUI) and Fallopian tube sperm perfusion (FSP) in the treatment of infertility. Ninety-six consecutive patients with infertility in 100 cycles were included in the study. Those randomized to standard IUI included 48 patients in 50 cycles [25 clomiphene citrate only and 25 clomiphene citrate/human menopausal...
متن کاملبررسی شیوع پاتولوژی لوله‌های رحمی در بیماران مبتلا به نازایی اولیه و ثانویه، بر اساس یافته‌های هیستروسالپنگوگرافی Evaluation of the Prevalence of Fallopian Tube Abnormality in Primary and Secondary Infertility Based on Hysterosalpingography Findings
Abstract Background & Aim: Infertility is a relatively common problem, the prevalence of which is reported to be one in six couples. Among female factors, ovarian and tubal factors which are treatable are the most important ones. Laparascopy is the golden test for evaluation of fallopian tubes but because of its expensiveness, the necessity of general anesthesia and other problems, hystero...
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ورودعنوان ژورنال:
- Fertility and sterility
دوره 76 6 شماره
صفحات -
تاریخ انتشار 2001